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They are characterized by extreme spatiotemporal heterogeneity, as instead of possessing a single unique structure, they exist as dynamic, interconverting ensembles of multiple conformations

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Those suffering from anaemia caused by B12 deficiency are likely to experience fewer symptoms, such as breathlessness and weakness, during this period

Clinically significant vitamin B 12 deficiency and megaloblastic anemia are unlikely, unless these drug therapies are prolonged for two or more years, or if in addition, the person's dietary intake is below recommended levels