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Excitotoxicity mediated GABAergic cell loss, downregulation of glutamate acid decarboxylase enzyme, upregulation of gamma-aminobutyric acid (GABA) transporters, overactivation of glutamate receptors are some of the key evidence for hypoactive inhibitory tone contributing to CNP and spasticity post-SCI

N-Acetyl-Cysteine: Modulating the cysteine redox proteome in neurodegenerative diseases

In tal senso, numerosi studi clinici hanno evidenziato lefficacia terapeutica della LAC in tipi diversi di neuropatie periferiche, quali: _ il tunnel carpale, _la neuropatia diabetica dolorosa, _neuropatie dei distretti cervico-brachiale e lombosacrale

doi: 10.26355/eurrev_202112_27335

This sustained activation amplifies cytokine production and exacerbates oxidative stress damage [15]