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Specifically, in a clinical study it was shown that the additional intake at a dose of 1000 mg/day: [7] significantly reduced oxidative stress increased the activity of antioxidant enzymes in patients with coronary artery disease

It is also found in foods like spinach, broccoli, and liver

To achieve blood levels of at least 30 ng/mL, adults living at temperate latitudes (think: anywhere with distinct seasons) need 800 to 1,000 IU per day, ideally from vitamin D3, which is more effective than D2