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He rejected out of hand the notion that chlorpromazine binds PrP C , and pointed out that cell biologists use chlorpromazine as an inhibitor of endocytosis, so that has to be the way it works for prions

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[DOI] [PMC free article] [PubMed] [Google Scholar] 47

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What is Coming in AML Therapy

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Limitations of animal research: Rat healing faster than human, young research animals heal better than aged humans, controlled injury models don't replicate complex human injuries perfectly, dosing conversions uncertain (body weight scaling imperfect), immune system differences affect inflammation and healing

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doi: 10.1038/cdd.2008.10 250 AshleyDHernandezJCaoRToKYegiazaryanAAbrahemRet al

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