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FEMS Microbiol Ecol 2015, 91

In addition to the markers mentioned above, the level of GPT2 can be used to identify those patients with NSCLC who will benefit the most from the treatment with GLS inhibitors (61)

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For example, NAPQI, the toxic metabolite, is primarily the product of CYP2E1 metabolism, and there is evidence that younger children have a relative immaturity in CYP2E1 metabolism, which would substantially reduce the production of this toxic metabolite in infants