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Nature Reviews Endocrinology, 16(3), 135-146

These systemic effects are uncommon and typically mild
These stubborn areas are characterized by several factors including high alpha-2 adrenergic receptor density relative to beta receptors, reduced blood flow, and greater insulin sensitivity leading to efficient fat storage

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2 PMC (2024)NNMT inhibition mitigates obesity-related metabolic dysfunctions in animal models
