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The trial was approved by the Intermountain Healthcare Institutional Review Board (IRB 1050163), registered in May 2016 at clinicaltrials.gov (NCT02770313), enrollment began in November 2016, and the final subjects 26-week visit was 19 February 2020

Compared with earlier GHRPs such as GHRP2 and GHRP6, ipamorelin displays a distinct selectivity profile: experimental work has shown that, at concentrations effective for stimulating growth hormone release, it does not trigger adrenocorticotropic hormone (ACTH) or cortisol secretion

CG typically consists of a mixture of 18- and 18-glycyrrhizin, often combined with glycine and cysteine to enhance efficacy and reduce side effects (Wen et al., 2021)

Similarly, a study by Xia et al

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