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Conclusions Physical and psychosocial PROMs diverge in people with MS 55 years and older as they age, with increased physical limitations but improved mental health over time

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There is not as much evidence regarding long-term efficacy or safety of gel vitamin B12 compared to injections, but at this time it appears B12 gel works similarly to raise blood levels

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This makes it relevant for forehead lines, crow feet, and other expression-related wrinkles