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This route is preferred by low molecular weight hydrophilic compounds such as small peptide fragments generated from the breakdown of proteins

Transient opening of the mPTP, a pore in the mitochondrial inner membrane, was induced in HCM (7,500 cells per well) with 10 M DOX

Furthermore, chromen-based compounds have also been shown to influence the tumour microenvironment and improve the efficacy of other therapies 20,21

CYP2E1 is localized in liver mitochondria instead of the endoplasmic reticulum

37 Of the two, OH has been demonstrated as the key reactive oxygen species to cause pulmonary edema during acute lung injury