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The primary function of hemostasis is the generation of a stable clot in the event of vascular injury, thereby preventing excessive blood loss

Even if NP is not fully contained, the disc organ may remain at least partially functional
It also means that the dose-response curve is steeper, which reinforces why accurate calculation and gradual escalation are non-negotiable

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doi: 10.1016/j.biomaterials.2014.12.050 110 MavrommatisEShiouraKMLosTGoldspinkPH
