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Recent studies have investigated the effects of antioxidant supplementation on stored RBCs for transfusion
However, the wide range of other activities that many IRE1 targeting compounds have may increase the risk of off-target effects, and thus this may limit their clinical application
10.1177/0884533611416127 [DOI] [PubMed] [Google Scholar] Bug M, & Meyer H (2012)
2014 Apr;27(4):586-95
