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Tanshinone IIA promotes the apoptosis of fibroblast-like synoviocytes in rheumatoid arthritis by up-regulating lncRNA GAS5

Naranbhai V, Altfeld M, Karim SS, Ndungu T, Karim QA, Carr WH

Anastrozole is a type of nonsteroidal aromatase inhibitor

Other non-brain tissues, including multiple fat pads, hindlimb skeletal muscles and liver were also collected, snap-frozen in liquid nitrogen and stored at 80 C before use

Mice were randomly assigned to two groups: a control (vehicle) group maintained on a normal rodent diet without drug administration, and a treatment (Luseo) group that received luseogliflozin (0.01% in chow, 15 mg/kg BW/day) in a normal rodent diet for 2 weeks prior to I/R until sacrifice