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This step leads to PKA activation and allows it to phosphorylate several target proteins including members of the mitogen-activated protein kinases (MAPKs) family

Shehata, H

PMID: 32906090

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Inhibition of ferroptosis to alleviate renal fibrosis: Studies indicate that targeting ferroptosis specifically with certain inhibitors can mitigate kidney damage and renal fibrosis: (1) In a 5/6 nephrectomy-induced CKD rat model, deferoxamine alleviates kidney injury and fibrosis by regulating iron metabolism and the TGF-1/Smad3 pathway (199)