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biological effects in humans or animals
Fibromyalgia serves as the quintessential example, also observed in patients with early or advanced cirrhosis

Barn-Mendoza I, Gonzlez-Arenas A

Both disorders are extremely rare and symptoms can be intermittent, often confounded by coexisting conditions

Additionally, among 42 men who underwent liver resection for HCC between 1995 and 1999, those whose preoperative testosterone levels were in the upper half of the distribution had greater disease recurrence and poorer survival rates over 5-year follow up (Lin 2007)
