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This integrated modulation not only helps to counteract acute oxidative stress but also establishes a long-term cellular environment that is more resistant to the deleterious cascades leading to ferroptosis, ultimately contributing to enhanced neuronal resilience (Table 3)

doi: 10.1017/S0031182004005943 124 CurtisJMinchellaDJ

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Consistently, postmortem striatal brain tissue from three patients with PD exhibited elevated FTH1 and IL-8 expression, closely recapitulating the transcriptional profile of microglia in the in vitro model