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Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors

Myokines, including interleukin-6 (IL-6), irisin, and brain-derived neurotrophic factor (BDNF), released in the context of muscle contraction, exert influence on CNS functioning by traversing the bloodbrain barrier (BBB) or by acting upon peripheral nerves

13 Researchers found improvements in sural nerve conduction velocity and amplitude, and improved neuropathic pain symptoms that were similar in both treatment groups and were significant when compared with placebo

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It helps neutralize free radicals, protects cells from oxidative stress, and may contribute to reducing the effects associated with premature cellular aging