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In our study, we for the first time identified cancer driver genes and genes playing key roles in oncogenic pathways induced by CR perturbation of cellular composition, tissue homeostasis and metabolic reprogramming, leading to cell proliferation of epithelium mucosa and global depletion of immune system control

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[24] Low alkaline phosphatase (ALP) on a blood test can provide an indirect indication of zinc deficiency (the optimal range for alkaline phosphatase is 70-90 IU/L)
