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In addition, by releasing some growth factors, the downstream signaling pathways (such as TGF-/Smad, PI3K/Akt, MAPK, etc.) are activated to promote the occurrence and progression of tumors (74)
The NF-E2 p45 and Nrf2 transcription factors are soluble proteins, whereas upon translation Nrf1 and Nrf3 are initially anchored in the endoplasmic reticulum (ER) as glycosylated proteins [8183]
B max means the maximum binding sites of synthesized peptide on glutathione Speharose 4B beads (mol peptide/mol glutathione)

doi: 10.2147/IJN.S155593, 77
