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These enzymes require the TCA cycle intermediate -KG for their enzymatic function, while the TCA cycle intermediates succinate and fumarate are competitive inhibitors (30)

Some individuals experience nausea and stomach upset when taking oral supplements

Biomedicines 10(12):3051 Munteanu IG, Apetrei C (2021) Analytical methods used in determining antioxidant activity: a review

Li M, Xiong J, Yang L, Huang J, Zhang Y, Liu M, et al

36,37 PEI is also useful for a DNA vaccination complex system, consisting of a tumor-specific antigen termed Dickkopf-1 (DKK-1) and the immune checkpoint termed programmed death-ligand 1 (PD-L1) complexed with poly-(lactic-co-glycolic) acid/ PEI (PLGA/PEI)