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The lowest effective dose should be used
The Future in (y)our Hands Be the Game Changers

Ohtori, S., Inoue, G., Miyagi, M

Joseph NM, He S, Quintana E, Kim YG, Nez G, Morrison SJ

Individuals with Raynauds disease experience exaggerated vascular responses to cold that can cause tissue damage and should avoid cold therapy
