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Description
While older studies have suggested that low As2O3 supplementation suppresses autophagy (250), more recent data have demonstrated the induction of autophagic cell death in INS-1 cells or HepG2 cells following NaAsO2 or As2O3 treatment (251)

F., Thorn T

In contrast, inositol phosphate metabolism was upregulated in ASD, helping to distinguish it from the control group with an AUC of 0.83, suggesting its potential as a diagnostic marker

The initial manuscript draft was undertaken by EI and KK

From these results we can assume ozone therapy influenced positively the synthesis and release of cytokines (14,15) in such away that a change from Th2 to Th1 [IL-2, IFNg] pattern occurs, reducing the production of asthma mediators [IgE, HLA-DR, etc]
