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During high-intensity cycling, the subjects taking L-carnitine had lower levels of lactic acid and higher levels of creatine phosphate, one of the primary building blocks of ATP

Austria, R., Semenzato, A

The NLRP3 inflammasome, closely related to CRC, is activated by TMAO-induced endothelial inflammation mediated by mitochondrial reactive oxygen species (ROS) (Yue et al., 2017)

Moreover, red hair was linked to higher CRP, but even if the possibility of hair dye causing this were inconclusive, another study on mice found that repeated exposure to hair dye induces regulatory T cells, whereas other data indicate that the removal of pubic hair can be a possible risk factor for unspecific low-grade inflammation [1081,1082,1083,1084]

This review explores the relationship between gut microbiota metabolites and CVDs, focusing on atherosclerosis and hypertension, and analyzes personalized microbiota-based modulation interventions, such as physical activity, diet, probiotics, prebiotics, and fecal microbiota transplantation, as a promising strategy for CVD prevention and treatment