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While a low peak GH concentration ( 2.5 SD above mean but in 2 patients surprisingly they were low at -2.5 and -0.2 SD

Blocking the interaction between CXCR4/CXCL12 effectively compromised the homing of LSCs into the BM niche and rendered leukemia cells sensitive to chemotherapy (182)

Briefly, RNA was isolated following the standard Trizol protocol and RNA oncentrations were obtained using the Qubit RNA Broad Range kit

In tumor cells, abnormal methylation leads to the activation of some important proto-oncogenes, leading to tumor suppressor gene silencing, genomic instability, and chromatin changes

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