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In the community the most common regimen is generally 10 mg per day, while clinicianderived protocols advise 510 mg daily subcutaneously, often run in a 2 to 6week cycle, though timing and cycling are rarely specified

I.MartinezA.NilsenF.DondrupM

doi: 10.3390/gels9020130 [DOI] [PMC free article] [PubMed] [Google Scholar] 125.Mura P, Mennini N, Nativi C, Richichi B

doi: 10.1111/j.1471-4159.1984.tb09689.x

Tumor heterogeneity, characterized by the presence of multiple clones, increases the likelihood of drug-resistant clones, resulting in treatment failure or recurrence
