glutathione reductase purpose Pathways Role of glutathione reductase (GR)
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C., Wolfe M

Tyrosine metabolism and immune cell differentiation Tyrosine metabolites, such as catecholamines (including epinephrine and norepinephrine), play an important role in the differentiation and function of immune cells

10.1016/j.molmet.2020.100978 Mol

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Notably, no increased apoptosis was seen in HCT116 GSTA4 cells regardless of increased ROS, implying that inactivation of GSTA4 mildly increases ROS that might promote proliferation
