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In the immediate aftermath of radiotherapy, DAMPs mediate the chemotaxis of neutrophils and macrophages from circulation to sites of lung tissue damage [11]

Other recognized but rare complications of overdose include heart block, pancreatitis, acute renal failure, alopecia, leucopenia, thrombocytopenia, anaemia, optic nerve atrophy and acute respiratory distress syndrome [18, 50]

1 2 3 4 5 6 "Pharmacomicrobiomics: the impact of human microbiome variations on systems pharmacology and personalized therapeutics"

Except for targeting mutant IDHs, metabolic inhibitors are potentially active regardless of tumor genetic subtype and thus beneficial to the large majority of men with CRPC who are not currently candidates for precision medicine (e.g., DNA repair defects for PARP inhibitors or CDK12 loss for immunotherapy) (138, 163)