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No evidence supports cycling versus continuous use, and no studies have determined optimal treatment duration

The gastrointestinal side effects result directly from the drug's mechanism of slowing gastric emptying and affecting gut motility

doi: 10.1016/s0168-3659(02)00019-6

Capurro, M., Martin, T., Shi, W

It cautions against the usage of the original Interpolated algorithm in WRF-Chem for simulating aerosol optical properties and their impacts on meteorological fields, which has some biases, particularly for regions with a large contribution from dust
