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This is why, at the beginning of the 20th century, when it was discovered that eating liver improved patients with pernicious anemia, they had to eat huge amounts to achieve a pharmacological effect. In these cases, we find an approximate absorption of, with luck, between 1-2% of the dose administered, but it is not uncommon for it to be even lower (0.5%) depending on the size of the dose, previous reserves, and other factors and individual conditions of each subject

After quality control, DNA libraries were constructed and sequenced to a target depth of 100 for all samples on the Illumina HiSeq platform

Hum Reprod 27:13001313 Zheng Q, Wang J, Li W, Chen X, Chen S, Chen L (2020) Emodin reverses the epithelial-mesenchymal transition of human endometrial stromal cells by inhibiting ILK/GSK-3beta pathway

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