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Studies of -carbolines in coffees are confounded significantly due to the common issues of studying coffee (cultivar, soil and inputs, growing conditions, processing methods, drying methods, storage time, roast level, etc.), but seem to have even wider swings of results than other compounds

CNS Spectr 12:73944, PMID: 17934378 Liu J (2008) The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview

Individuals with IBD who were treated with anti-TNF biologics as part of their chronic anti-inflammatory regimen had a 78% lower risk of developing PD than those who did not get this medication (102)

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