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GSH depletion is necessary for the formation of the apoptosome [124] and also triggers cell death by modulation of the permeability transition pore of the mitochondria and the activation of executioner caspases [125,126]

Hy vng bi vit trn y cung cp cho b m nhiu kin thc b ch, hiu r Glutathione c tc dng g
To maintain continuous antioxidant defenses, the cell must recycle this oxidized molecule

Pb impairs both GABA uptake and depolarization-evoked release in synaptosome preparations, likely through reduced expression of glutamate decarboxylase (GAD) and compensatory upregulation of GABA transporter 1 (GAT-1) [47,48,71]

Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment
