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Yubero-Lahoz et al., 2011)

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However, it has also been reported that the PPP flux decrease may be an early event in the pathogenesis of sporadic PD, because in the later stages of PD, PPP flux is up-regulated in an attempt to counteract persistent oxidative stress [117]

Immunoblotting of phospho-Rb Protein lysates were processed following standard procedures and analysed by SDS-PAGE followed by immunoblotting