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To determine if the changes in astrocyte morphology impacted bloodbrain barrier coverage, socially defeated mice were injected 24 h after their last stress session with a fluorescently tagged dextran that is unable to cross the bloodbrain barrier under normal conditions and examined if this signal was present in the ME/ARC of these mice in comparison with similarly injected nonstressed mice

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A stable and reproducible human bloodbrain barrier model derived from hematopoietic stem cells

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