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J Biol Chem 287:36303641

82 Besides, drug-induced ROS can inhibit the PI3K/AKT pathway to suppress cancer cell proliferation by disrupting key pathways critical for tumor growth and survival, as evidenced by studies with (+)-anthrabenzoxocinone in NSCLC and 6-methoxydihydrosanguinarine in breast cancer

In p21-deficient tumor cells exposed to DNA-damaging agents, apoptosis occurs rapidly, whereas cells with enforced p21 expression survive despite accumulating damage 32

Eur J Cancer

Increased glutathione level results in salt stress tolerance and global translational changes in Arabidopsis
