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The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohns disease

Carnitine may reduce nerve damage symptoms associated with paclitaxel use

The resulting GABA then potentially affects the brain via the vagus nerve via the gut-brain axis or by increasing GABA levels in the blood

D., Sumner, D

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