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Endothelial dysfunction is characterized by the reduction of bioavailability of NO, resulting in impaired endothelium-dependent vasodilation (69) and increased oxidative stress (70)

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Morningness-Eveningness Questionnaire The MEQ was developed by Horne and Ostberg in 1976

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Various parts of allium plant (i.e., leaves, flowers, pseudostem, bulb, and seeds) are consumed in different forms due to their versatility

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2023;15(700):eadd1531

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Week 1: Dose: 50mcg Frequency: Once, on a night when you can sleep in the next morning Timing: 2-3 hours before intended sleep Purpose: Assess basic tolerance and response Week 2: Dose: 75-100mcg Frequency: 2-3 times during the week Timing: 1-2 hours before bed Purpose: Establish baseline effective dose During this assessment phase, track sleep quality subjectively and, if possible, with a wearable device that measures sleep stages

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