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Not only do we need to adopt a personalised approach to patient-centred care, we need to appreciate the need for a holistic approach to medicine
GPX3 is an extracellular glycoprotein that accepts thioredoxin (Trx) and glutaredoxin (Grx) as substrates in addition to GSH [13]
This review also discusses the regulation of amino acid metabolism in cancer, therapies that are under investigation, and aspects of amino acid metabolism relevant to inhibition with a specific focus on transaminases and amino acid transporters
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