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Keloid Senescent Fibroblast Elimination & SASP Suppression (Communications Biology, 2025) FOXO4-DRI Induces p53-pS15 Nuclear Exclusion and Apoptosis in Keloid Fibroblast Models A study published in Communications Biology (Nature Publishing Group, 2025) used single-cell RNA sequencing to characterise the senescent cell landscape in keloids pathological scars with tumour-like aggressiveness

Library preparation and sequencing were performed, followed by the trimming of sequence reads using fastp v.0.23.13 to remove potential adaptor sequences and low-quality nucleotides

The name Trinity-X refers to its triple-receptor mechanismthree pathways activated by one molecule

Nrf2 signaling pathway is an important way to regulate cellular oxidative stress, which plays an important role in DILI (Tong et al., 2006)

Semax is generally chosen for focus, motivation, and clearing brain fog, while Selank is often described as the more directly calming, anti-anxiety option