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Description
Not approved for therapeutic, diagnostic, or clinical applications

Food-cobalamin (vitamin B 12 ) malabsorption, first described by Carmel in 1995,30 is the most common cause of vitamin B 12 deficiency in the elderly and accounts for about 40% to 70% of cases.26 29 31 It is characterised by the inability to release vitamin B 12 from food or from its binding protein and thus, preventing vitamin B 12 from being taken up by intrinsic factor for absorption

Current clinical trials show AOD9604 has a good safety profile

Relationship to the GH-IGF-1 Axis Because this fragment does not appear to stimulate IGF-1 production in laboratory models, it provides researchers with a tool to study the IGF-1-independent aspects of GH signalling in metabolic biology

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