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Concurrently, an elevation in the levels of key lipolytic receptors, specifically beta-3-adrenergic receptors within adipocytes, was observed in these models

The Therapeutic Goods Administration (TGA) in Australia granted it Generally Recognized As Safe (GRAS) status for use in foods at one point, but that classification does not transfer to injectable compounded preparations in the United States [2]

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Critically, these effects were absent in 3-AR knockout mice, indicating that an intact 3-AR pathway is required for the lipolytic activity