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These include how bad your deficiency is, how you react to treatment, and the method of injection

Her eczema had spread to the soles of her feet and even though she was only in her early 20s she was hobbling around like an old lady

(PubMed) Obeid R

IV infusions deliver B12 intravenously through a catheter placed in a vein

In fact, one study found that peoples bodies absorbed about 49% of a 1-mcg dose of cyanocobalamin, compared to 44% of the same dose of methylcobalamin ( Conversely, another study comparing the two forms reported that about three times as much cyanocobalamin was excreted through urine, indicating that methylcobalamin may be retained better within your body ( However, some research suggests that differences in bioavailability between the two forms may be insignificant and that absorption could be influenced by factors such as age and genetics ( Unfortunately, recent research directly comparing these two forms of vitamin B12 is limited