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[20] [21] Proton pump inhibitors (PPIs) such as omeprazole can reduce B12 absorption and may cause digestive upset

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Ipamorelin, a synthetic pentapeptide, appears to act as a selective agonist for the ghrelin receptor and may stimulate the release of GH

PLoS ONE 10:e0130908

It also depends on how the patient responds to the initial therapy
