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In brief, N275 treatment stimulated hepatic de novo lipogenesis by upregulating Srebp1c , Ppar , and Fas , while N800 treatment inhibited Srebp1c , Ppar , and Chrebp but maintained de novo lipogenesis

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Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension