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Moreover, while OCCC show intrinsic resistance to conventional platinum-based chemotherapy, OSC exhibit at first sensitiveness to platinum-based chemotherapy, though the majority of cases develop chemoresistance during the course of treatments 33,34

Considering the clinical values of tamoxifen in treatment of breast cancer, it is clear that preventing and overcoming tamoxifen resistance remains important clinical goals

Artificial ligand binding within the HIF2 PAS-B domain of the HIF2 transcription factor

Solutions of TP with varying concentrations (50, 100, and 140 mg/mL) were prepared and found to have desirable spray characteristics and large coverage of the nasal cavity surface area when delivered as a nasal spray

However, this research involved extremely high doses of fish oil combined with an overall inflammatory diet composition
