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Rat chow consumption and body weights The chow consumption of rats significantly decreased in the MTX group compared with the control group

stable for up to 24 months

Pharmacokinetics of pyrazinamide and its metabolites in healthy subjects

Ferrous ion has the effect of mediating ROS production and enzyme activity during lipid peroxidation, which can produce a large number of ROS through the Fenton reaction (Dixon et al., 2012), and it also increase the activity of lipoxygenase (LOX) or EGLN prolyl hydroxylases, which are responsible for lipid peroxidation and oxygen homeostasis ( The System X c /GSH/GPX4 axis is an important antioxidant system ferroptosis
