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There are also inhibitors of closely related pathways, for instance, wortmannin, LY294002, and 3-methyladenine inhibit PI3K, blocking autophagosome formation [Wu & Tan 2010]
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The elevated calcium influx impaired GSH production and subsequently diminished GPX4 activity, setting up a reduced capacity of Xc/GSH/GPX4 antioxidant defence system
D.OriasE.PearsonC
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