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The unbalanced regulation of two enzymes in the same cycle suggests that an alternative pathway exists to convert GSSG back to GSH

Role of copper transport protein antioxidant 1 in angiotensin II-induced hypertension: a key regulator of extracellular superoxide dismutase

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Furthermore, LCs ability to regulate fatty acid oxidation affects systemic inflammation and immunological responses, as metabolites such as SCFAs can influence immune cell activity and gut barrier integrity [9, 4447]

Nevertheless, several more recent large cross-sectional studies reported a significant inverse correlation between blood pressure and IGF-1 (123, 191196)