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Free radicals are unstable because they are missing an electron and they seek the electron in other molecules, which results in damage

The physiological GSH:GSSG ratio is not able to promote the formation of PSSG

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4 Current challenges and prospects 4.1 Therapeutic targeting potential of TGF- 4.1.1 TGF- downstream effectors The therapeutic targeting of TGF- and its downstream effectors, particularly the Smad proteins, presents a promising avenue in fibrosis treatment