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Patients (and caregivers of patients) should be informed that AEDs increase the risk of suicidal thoughts and behavior and should be advised of the need to be alert for the emergence or worsening of the signs and symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior, or thought about self-harm

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Safety Information Store the powder in a cool and dry place

The remainder of this review will discuss the pathophysiology and clinical features of CRF, evidence-based treatment approaches, current guideline recommendations from oncology and psychiatry perspectives, and future directions in research and care