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These medications work through different receptor mechanisms, have different pharmacokinetic profiles, and produce different physiological responses at every dose level

Alpha-adrenergic blockade improves glucose-potentiated insulin secretion in non-insulin-dependent diabetes mellitus

Eye 26 (8), 10441051

An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD(+) imbalance

35 S-Labeling studies performed in vivo show that phosphatidylethanolamine is a major small-molecular-weight nucleophile thioacylated in mitochondria by the action of cysteine S -conjugate -lyases on TFEC (Hayden et al., 1992)