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4 Immune and metabolic crosstalk in the regulation of ferroptosis Beyond metabolic changes, immune components significantly influence ferroptotic events in OA

Age-related reductions in reproductive hormone levels, testicular function, chromosomal integrity, and sperm health, as well as increased oxidative stress and cumulative damage to sperm DNA, all contribute to reduced fertility

Rodriguez AE, Ducker GS, Billingham LK, Martinez CA, Mainolfi N, Suri V, et al

For more information about this advisory, kindly contact the FDA Center for Food Regulation and Research via e-mail at [email protected],

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